Protease for Challenging Protein Digestions. A highly-purified serine protease that hydrolyzes specifically at the carboxyl side of lysines. Lys-C retains proteolytic activity under strong protein denaturing conditions such as 8M urea, which can be used to improve digestion of proteolytically resistant proteins.
- Generates longer peptides than with tryptic protein digestion
- C-terminal (Lys-C) lysine cleavage
- Active under strong denaturing conditions
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