Epigenetik
Produkter och metoder för studier av epigenetiska förändringar i laboratoriemiljö. Fokus ligger på analys av genreglering som inte involverar förändringar i DNA-sekvensen, exempelvis DNA‑metylering och histonmodifieringar.
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Active Motif
Recombinant Histone H3K4me1 (MLA)
Recombinant Histone H3K4me1 (MLA) has been generated using the patented Methylated Lysine Analog (MLA) technology. In MLA, methylated histones are generated via a chemical alkylation reaction that substitutes a methylated analog of lysine, aminoethylcysteine, for the existing lysine at the desired residue.31719-AF -
Active Motif
Spike-in Chromatin
Active Motif's ChIP Spike-in Normalization Strategy can be used to normalize ChIP qPCR and ChIP-Seq data to reduce the effects of technical variation and sample processing bias.53083-AF -
Active Motif
Total Histone H3 ELISA
Histone Modification ELISAs provide a simple, sensitive method for detecting changes in histone methylation levels from purified core histones or histones isolated by acid extraction. For added convenience and a more quantitative interpretation of results, the Histone Modification ELISAs also include a site- and degree-specific methylated recombinant histone protein for use as a reference standard curv53110-AF -
Active Motif
TransAM NFkappaB p52
TransAM® kits are sensitive, non-radioactive transcription factor ELISA-based assays that facilitate the study of transcription factor activation in mammalian tissue and cell extracts. These optimized assays are available for many different transcription factors48696-AF